
GU Cast | Urology Podcast
A urology podcast, focussing on all things prostate, kidney, bladder, testis and penile cancer. Join Professor Declan Murphy and Dr Renu Eapen from Peter MacCallum Cancer Centre in Melbourne for this regular dive into the world of genitourinary (GU) Oncology and Urology. Regular guests from all over the world, from every walk of life. Find out more gucast.org
GU Cast | Urology Podcast
Do MRI-targeted prostate biopsies lead to over-diagnosis and over-treatment??!!
Well the data are clear, says eminent biostatistician and research methodologist, Dr Andrew Vickers of Memorial-Sloan Kettering Cancer Centre in New York. In some well constructed recent articles, Andrew has really made us think again about the impact of moving to MRI-directed triage and targeted biopsies, instead of "blind" systematic biopsies. Could it be that this strategy actually leads to harm, rather than the clear benefits which many assume that MRI has brought to prostate cancer diagnostics??
We are joined today by Andrew, and two household names in the world of MRI-targeted biopsies to defend the practice (which is now recommended by all major guidelines). Professor Caroline Moore, Urologist at University College London, and Dr Veeru Kasivisvanathan, Urology Fellow at Peter MacCallum Cancer Centre in Melbourne. Veeru and Caroline were first and senior authors on the landmark PRECISION trial published in NEJM in 2018 which led to the adoption of MRI in early detection of prostate cancer.
And Dr Renu Eapen is back from her travels and in her usual co-hosting role, along with Professor Declan Murphy. Plus Dr Aoife McVey returns to tell us what caught her eye on twitter this week. A cracking episode!
Also posted on Youtube here
Links:
Dr Andrew Vickers Twitter
Professor Caroline Moore Twitter
Dr Veeru Kasivisvanathan Twitter
Dr Aoife McVey Twitter
@Urology_tips Twitter
Dr Laura Bukavina Twitter
Andrew's recent European Urol article on the harms of MRI-targeted biopsies ($)
Renu's ASCO GU talk